Test Overview
Test Usage

Recommended for investigation of: 1) a patient with suspected or proven thymoma, whether or not symptoms or signs of MG are present (also of value for serially monitoring patients after removal of thymoma; a rising autoantibody titer may herald tumor persistence or recurrence), or emergence of an unrelated neoplasm and 2) a bone marrow transplant recipient with suspected graft-vs.-host disease, particularly if there is evidence of weakness.

Reference Range *

Muscle AChR Binding Ab: <=0.02 nmol/L; Muscle AChR Modulating Ab: 0 - 20%; Striational Ab: <1:120; CRMP-5-IgG Western Blot: Negative; AChR Ganglionic Neuronal Ab: <=0.02 nmol/L; Glutamic Acid Decarboxylase Ab: <=0.02 nmol/L; Voltage-Gated Potassium Channel Ab: <=0.02 nmol/L.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Analytic Time

3 - 7 days

Soft Order Code
MMLR
Synonyms
  • ACh Receptor (Muscle) Binding Antibody
  • ACh Receptor (Muscle) Modulating Antibody
  • AChR Ganglionic Neuronal Antibody
  • CRMP-5 IgG
  • Striational (Striated Muscle) Antibody
  • AChR Antibodies
  • Acetylcholine Receptor Antibodies
  • GAD65 Antibody
  • Neuronal (V-G) K Channel Antibody
Laboratory
Sendout
Reference Laboratory
Mayo MGT1
Section
Special Testing
Test Updated
Update Type
Test Resumed
Specimen Requirements
Collection Instructions

Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Yellow Top Tube
Normal Volume
3 mL serum
Minimum Volume
2 mL serum
Additional Information

Evaluation includes the following tests: AChR Binding Ab, AChR Modulating Ab, Striational Ab, AChR Ganglionic Neuronal Ab, CRMP-5-IgG Western Blot, Glutamic Acid Decarboxylase Ab (GAD65), and Voltage-Gated Potassium Channel Ab. Test sent to Mayo Medical Laboratories.

Billing
CPT Code
83519 x4, 83520, 84182, 86341
Reflex CPT
GAD65 86341, VGKC 83519
Reflex Fee Code
GAD65 32140, VGKC 40393
Resources