Analytic Time

3 - 7 days

Soft Order Code

Test Updated:


Acetylcholine Receptor Antibodies
ACh Receptor (Muscle) Binding Antibody
ACh Receptor (Muscle) Modulating Antibody
AChR Ganglionic Neuronal Antibody (reflex)
CRMP-5 IgG (reflex)
Striational (Striated Muscle) Antibody
AChR Antibodies
P/Q Type Calcium Channel Antibody
N Type Calcium Channel Antibody
CRMP-5-IgG Western Blot, S
AChR Ganglionic Neuronal Ab, S

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Test Overview

Test Methodology
Test Usage

Recommended for patients presenting with an acquired defect of neuromuscular transmission in whom the differential diagnosis includes LES. It is not recommended for patients with a past history of, or risk factors for, lung cancer and/or concurrent neurological symptoms/signs not attributable to LES; for those situations, order Paraneoplastic Autoantibody Evaluation (Mayo 83380). Testing for a newly recognized alternative antibody of MG (muscle-specific receptor tyrosine kinase [MuSK]) is indicated when all tests are negative. MuSK antibody testing is available on request.

Reference Range

Muscle AChR Binding Ab: <=0.02 nmol/L; Muscle AChR Modulating Ab: 0 - 20%; Striational Ab: <1:120; P/Q Type Calcium Channel Binding Ab: <0.02 nmol/L; N Type Calcium Channel Binding Ab: <0.03 nmol/L; CRMP-5-IgG Western Blot: Negative; AChR Ganglionic Neuronal Ab: <=0.02 nmol/L.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Collect specimen in a red top tube.

Collection Offsite

Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Yellow Top Tube
Normal Volume
3 mL serum
Minimum Volume
2 mL serum

Billing Information

CPT Code
83519 x4, 83520
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.