Test Overview
Test Usage

Recommended for initial investigation of: 1) a patient aged 20 or older with symptoms and signs of acquired MG; and 2) a bone marrow transplant recipient with suspected graft-vs.-host disease, particularly if there is evidence of weakness.

Reference Range *

Muscle AChR Binding Ab: <=0.02 nmol/L; Muscle AChR Modulating Ab: 0 - 20%; Striational Ab: <1:120; CRMP-5-IgG Western Blot: Negative; AChR Ganglionic Neuronal Ab: <=0.02 nmol/L; Glutamic Acid Decarboxylase Ab: <=0.02 nmol/L; Voltage-Gated Potassium Channel Ab: <=0.02 nmol/L.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details
Analytic Time

3 - 7 days

Soft Order Code
MiChart Code
Myasthenia Gravis (MG) Eval, Adult (Inactive)
  • MGEA
  • MG Evaluation, Adult
  • Neuronal (V-G) K Channel Antibody (reflex)
  • ACh Receptor (Muscle) Binding Antibody
  • ACh Receptor (Muscle) Modulating Antibody
  • Striational (Striated Muscle) Antibody
  • AChR Ganglionic Neuronal Antibody (reflex)
  • CRMP-5 IgG (reflex)
  • AChR Antibodies
  • Acetylcholine Receptor Antibodies
  • CRMP-5-IgG Western Blot, S
  • AChR Ganglionic Neuronal Ab, S
  • GAD65 Antibody (reflex)
  • STR
  • C5BLOT
  • VGKC
  • Neuronal (V-G) K+ Channel Ab
Reference Laboratory
Mayo MGA1
Special Testing
Test Updated
Update Type
Test Resumed
Specimen Requirements
Collection Instructions

Collect specimen in a red top tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Red Top Tube
Normal Volume
3 mL serum
Minimum Volume
2 mL serum
Additional Information

Evaluation includes the following tests: AChR Binding Ab, AChR Modulating Ab, and Striational Ab. The following tests are reflexed at an additional charge when indicated: AChR Ganglionic Neuronal Ab (ACHRG), CRMP-5-IgG Western Blot (C5BLOT), Glutamic Acid Decarboxylase Ab (GAD65), and Voltage-Gated Potassium Channel Ab (VGKC). By ordering this test the clinician acknowledges that additional reflex testing will be performed and billed at a separate additional charge if indicated. Test sent to Mayo Medical Laboratories.

CPT Code
83519 x2, 83520
Fee Code
Reflex CPT
ACHRG 83519, C5BLOT 84182, GAD65 86341, VGKC 83519
Reflex Fee Code
ACHRG 36139, C5BLOT 36140, GAD65 32140, VGKC 40393