3 - 5 days
Update Type: Test Discontinued
Test Updated: 10/07/2020
C677T MTHFR Mutation
Methylenetetrahydrofolate Reductase by DNA Analysis
MTHFR Mutation Detection
Homocysteine Mutation Detection
A1298C MTHFR Mutation
Methylenetetrahydrofolate Reductase Mutation
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Direct mutation analysis using PCR amplification, signal generation, and release by cleavage of sequence-specific alleles.
Direct mutation analysis for the MTHFR C677T and/or A1298C mutations should be reserved for patients with coronary artery disease, acute myocardial infarction, peripheral vascular artery disease, stroke, or venous thromboembolism who have increased basal homocysteine levels or an abnormal methionine-load test.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Collect blood in a yellow top (ACD solution B) (preferred) or lavender top (EDTA) tube. Send intact whole blood specimen at room temperature (preferred) or refrigerated.