Days Set Up
Monday - Friday
Analytic Time

72 hours

MiChart Code
Monoclonal Gammopathy Evaluation
Soft Order Code
MGE2

Test Updated:

Synonyms

Gammopathy Panel
IFIX, Serum
Immunoelectrophoresis (IEP), Serum
Immunofixation (IFIX), Serum
Immunoglobulin Electrophoresis
Kappa Light Chains, Serum
Lambda Light Chains, Serum
Light Chains, Serum
Myeloma Proteins, Serum
MONOCLONAL GAMMOPATHY EVAL
IMMUNOFIXATION - SERUM
IFIX
IGS
TPE
IMFIXATION
IMMUNOFIXATION - SERUM
IMMUNOGLOBULIN QUANTITATION
PROTEIN ELECTROPHORESIS
IMMUNOFIXATION

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All specimens should be accompanied by a requisition.

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Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

Test FAQ

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Test Overview

Test Methodology

See individual tests.

Test Usage

To differentiate between monoclonal and polyclonal gammopathies. To identify and type monoclonal immunoglobulins for heavy and light chain specificity. Monoclonal gammopathy evaluation (MGE) is essential when clinical, hematologic, or pathologic findings indicate: multiple myeloma, Waldenstrom's, heavy chain disease, amyloidosis, or Ig deposition disease. MGE is also essential in the presence of abnormal bands on serum protein electrophoresis (TPE), in cryoglobulins, in Bence Jones proteinuria, in pyroglobulins, and in hyperviscosity syndrome. If light chain disease is part of the differential diagnosis, submit a urine specimen for Bence Jones Protein Screen.

Reference Range

Pathologist interpretation of results provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Collect specimen in an SST tube. Test includes serum protein electrophoresis, total protein, immunoglobulin quantitation (IgG, IgA, IgM) and immunofixation if indicated.

Collection Offsite

Collect specimen in SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.

Yellow Top Tube
Normal Volume
2 mL serum
Minimum Volume
0.6 mL serum

Billing Information

CPT Code
84165, 86334, 82784 x3, 83883 x2
Pro Fee Code
84165 TPE, 86334 IFIX
LOINC
 

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.