Days Set Up
Monday - Friday, 8:00am - 4:30pm; Saturday 8:00am-12:00noon
Analytic Time

8 - 48 hrs

MiChart Code
Minimal Residual Disease for B-ALL; Bone Marrow
Soft Order Code
MRDBM

Test Updated:

Synonyms
 

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All specimens should be accompanied by a requisition.

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Test Overview

Test Methodology

Flow Cytometry; multi-fluorochrome

Test Usage

This test is typically performed on bone marrow aspirate, day 29 post therapy. In patients with B-cell acute lymphoblastic leukemia (ALL), treatment response is evaluated with minimal residual disease (MRD) assays.

Reference Range

Pathologist interpretation of results provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Should be collected from a first pull aspirate (the person collecting the marrow should redirect the Jamshidi) into a heparinized syringe that will be transferred into a 7ml green top and thoroughly mixed
The following information is required on a Flow Cytometry requisition:
<ol><li>Relevant clinical history
</li><li>Clinical or morphological findings and suspicions
</li><li>Specimen source
</li><li>Date and time of collection
</li><li>Phone number and after hours pager number for ordering physician
</li></ul></ol>

Collection Offsite

The following information is required on a Hematopathology Consult requisition:
<ol><li>Relevant clinical history
</li><li>Clinical or morphological findings and suspicions
</li><li>Specimen source
</li><li>Date and time of collection
</li><li>Phone number and after hours pager number for ordering physician
</li></ul></ol>

<strong>BONE MARROW ASPIRATE:</strong>
<ul><li>Add 1 - 2 ml of first pull bone marrow aspirate to a green top sodium heparin Vacutainer® tube. Send intact specimen at room temperature within 12 hours of collection.
</li><li>Include 4 unstained aspirate smears
</li><li>Include an unstained peripheral blood smear
</li><li>Include a copy of the patient's most recent White Blood Cell and platelet counts, and peripheral blood differential.
</li></ul>

Normal Volume
<strong>BONE MARROW ASPIRATE:</strong> 1-2 ml
Minimum Volume
<strong>BONE MARROW ASPIRATE:</strong> 1 ml

Billing Information

CPT Code
88184, 88185 x11, 88188
Pro Fee Code
88188
LOINC
 

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.