Days Set Up
Varies; test performed twice per week
Analytic Time

8 hours

MiChart Code
Metanephrines, Plasma Fractions
Soft Order Code

Test Updated:


Normetanephrines, Plasma
Fractionated Metanephrines, Plasma
Metanephrines, Fract., Free, P

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Test Overview

Test Methodology

Tandem Mass Spectrometry (UPLC-MS/MS)

Test Usage

Screening test for presumptive diagnosis of catecholamine-secreting pheochromocytomas or paragangliomas.

Reference Range

Metanephrine, Plasma <0.5 nmol/L; Normetanephrine, Plasma <0.9 nmol/L.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements


Collect specimen in a lavender top tube. Centrifuge, aliquot plasma into a plastic vial and freeze. Discontinue epinephrine and epinephrine-like drugs at least 1 week before obtaining the specimen. The patient must fast and abstain from smoking tobacco for at least 4 hours before the specimen is drawn. The patient may drink only water during the fasting period.

Lavender Top Tube
Normal Volume
1 mL EDTA plasma
Minimum Volume
0.5 mL EDTA plasma

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.