Days Set Up
Monday - Friday, 8:00am - 5:00pm
Analytic Time

24 - 48 hours

Test Updated:


Miscellaneous Lesion Scraping Cytology
Tzank Smear Cytology
Tzanck Smear Cytology
Cytology, Non-Gyn

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All specimens should be accompanied by a requisition.

Submitting Specimens

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Test Overview

Test Methodology

Examination of glass slide(s) by light microscopy.

Test Usage

Lesion scraping cytology is used to detect the presence of neoplastic cells and/or infection and inflammatory agents.

Reference Range

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements


Label a glass slide with patient last name, first name and registration number (or other second unique patient identifier) using a graphite pencil (do not use ink, wax or crayon). Open the vesicle or lesion/ulcer with a sterile blade. Use the blade edge to gently scrape one edge of the lesion. Gently smear the scraped material onto the glass slide and fix immediately with spray fixative. Allow spray-fixed slide to dry completely and place into a slide holder. Submit with an appropriately completed requisition or electronic lab order, including source of the sample and pertinent patient history. Deliver to Specimen Processing or to the Cytopathology Laboratory during laboratory hours.

Collection Onsite

See instructions in Collection section.

Collection Offsite

See instructions in Collection section.

Minimum Volume

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.