INSULIN ANTIBODIES, SERUM
INSULIN ANTIBODIES, BEEF
INSULIN ANTIBODIES, HUMAN
INSULIN ANTIBODIES, PORK
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The presence of insulin antibody indicates either long-term insulin injection or autoimmune insulin antibody. Insulin resistance, defined as a state in which the daily insulin requirement exceeds 200 units/day for more than two days, may be associated with elevated anti-insulin antibody titers and insulin-binding capacity. Elevated insulin-binding alone, however, is not pathognomonic of insulin resistance, a complex phenomenon which may be due to a number of different causes such as ketosis or hormone antagonism. Stable diabetics, who are characterized as requiring infrequent changes in insulin doses, may have significant circulating concentrations of high avidity antibodies, whereas 'unstable' diabetics, who require frequent changes in insulin dose, may have lower concentrations.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Collect specimen in a red top or SST tube from a fasting patient.
Collect specimen in a red top or SST tube from a fasting patient. Centrifuge, aliquot serum into plastic vial and refrigerate. Grossly hemolyzed specimens are unacceptable.