Days Set Up
Monday - Friday, 8:00am - 4:30pm; Saturday 8:00am-12:00noon
Analytic Time

8 - 48 hrs

MiChart Code
Leukemia/Lymphoma Immunophenotyping; Blood, Flow Cytometry
Soft Order Code
LEUKB

Test Updated:

Synonyms

Leukemias, Acute
T and B Cell Typing for Lymphocytic Leukemias
Lymphocytic Leukemias, Acute and Chronic Subtyping
Lymphocyte Typing for Lymphoproliferative Disorders
Multiple Myeloma
Leukemia / Lymphoma Immunophenotyping
B and T Cell Typing for Lymphocytic Leukemias
Plasma Cell Panel (PCL)
Panel 3: Plasma Cell / Multiple Myeloma
Leukemias, Chronic
Chronic Lymphocytic Leukemia (CLL)
Mixed Linage Acute Leukemia
Acute Lymphocytic Leukemia (ALL)
Acute Myelogenous Leukemia (AML)
Leukemia/Lymphoma, Uncertain Subtype
ACUTE
NONACUTE
LEUKB
ACUTE MARKER PANEL
NONACUTE MARKER PANEL
COMBO
Leukemia/Lymphoma Workup
Prolymphocytic Leukemia (PLL)
Mantle Cell Lymphoma/Leukemia (MCL)
Hairy Cell Leukemia (HCL)
Non-Hodgkin's Lymphoma
Follicular Lymphoma
Diffuse Large B-Cell Lymphoma (DLBCL)
Leukemia/Lymphoma Acute Marker Panel
Leukemia/Lymphoma Nonacute Marker Panel
Leukemia/Lymphoma Combo Marker Panel
Panel 1: Stem Cell Neoplasm / Acute Leukemia
Panel 2: Mature Lymphoid Leukemia / Non-Hodgkin Lymphoma
Panel 4: Comprehensive Leukemia / Lymphoma

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Find a Requisition

All specimens should be accompanied by a requisition.

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Test Overview

Test Methodology

Direct immunofluorescence using flow cytometric techniques.

Test Usage

Confirmation of diagnosis and immunophenotype in acute and chronic leukemias and lymphomas. See http://www.pathology.med.umich.edu/handbook/Tables/Flow_Cytometry_Panel… for all Flow Cytometry Panels.

Reference Range

[link text="LEUKB AND IMM reference ranges.docx" href="/static/apps/handbook/Tables/LEUKB%20AND%20IMM%20reference ranges.docx"]
[bold]*Pediatric Reference Ranges from Journal of Allergy and Clinical Immunology, vol. 112, No. 5, 11/2003 and studies performed at Michigan Medicine Flow Cytometry Laboratory. Absolute ranges are calculated utilizing absolute lymphocyte count ranges for the same age groups provided by the hematology laboratory.[/bold]

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

The following information is required on a Flow Cytometry requisition:
[list order =Y]
Relevant clinical history
Clinical or morphological findings and suspicions
Date and time of collection
Phone number and after hours pager number for ordering physician
[/list]
[list]
Collect blood in a yellow ACD A or B Vacutainer® tube or green 7-10 ml sodium heparin Vacutainer® tube and transport at room temperature within 4 hours of collection.
A concurrent CBCD should also be ordered for the patient.
[/list]

Collection Offsite

The following information is required on a Hematopathology Consult requisition:
[list order =Y]
Relevant clinical history
Clinical or morphological findings and suspicions
Date and time of collection
Phone number and after hours pager number for ordering physician
[/list]
[list]
Collect blood in a green 7-10 ml sodium heparin Vacutainer® tube or yellow top ACD A or B Vacutainer® tube and transport at room temperature within 12 hours of collection.
Include a copy of the patient's concurrently drawn White Blood Cell and Platelet counts, peripheral blood differential and an unstained peripheral blood smear, OR, concurrently collect a lavender EDTA Vacutainer® tube for a CBCD to be performed upon receipt of the specimen.
[/list]

Normal Volume
[list]
Whole blood: (FULL) Yellow top ACD A or B Vacutainer® tube
Whole blood: 7-10 ml Green top sodium heparin tube
[/list]
Minimum Volume
Whole blood: 3 ml added to Green top sodium heparin tube

Billing Information

CPT Code
ACUTE: 88184, 88185 x23, 88189; NONPB: 88184, 88185 x14, 88188; COMBO: 88184, 88185 x22, 88189
Pro Fee Code
ACUTE: 88189.1, NONACUTE: 88188.3, COMBO: 88189.2
LOINC
Z501-7

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.