Days Set Up
Daily, 24 hours
Analytic Time

4 hours

MiChart Code
Homocysteine
Soft Order Code
HCY

Test Updated:

Synonyms

HOMOCYSTEINE
HCY

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All specimens should be accompanied by a requisition.

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Test Overview

Test Methodology

Chemiluminescent Assay

Test Usage

Assessment of risk for occlusive vascular disease, obstetric complications (recurrent spontaneous abortion, gross placental infarction), and neural tube defects (hyperhomocysteinemia). Patients taking methotrexate, nicotinic acid, theophylline, nitrous oxide or L-Dopa may have falsely elevated Homocysteine levels. S-adenosyl-methionine is an antidepressant that is structurally similar to S-adenohomocysteine. Individuals taking this drug may show elevated levels of Homocysteine.

Reference Range

5 - 15 mcmol/L. The population determined reference interval for homocysteine is 5-15uM. However, studies have shown a gradual increase in risk for atherosclerosis as homocysteine levels increase above 11 uM.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Collect blood in a lavender top tube from a fasting patient. Place on ice and deliver to laboratory within 30 minutes of collection.

Collection Offsite

Collect blood in a lavender top tube from a fasting patient. Centrifuge and aliquot plasma into plastic vial within 30 minutes of collection. Freeze (preferred) or refrigerate up to 2 days; specimens stored at room temperature are unacceptable.

Lavender Top Tube
Normal Volume
2 mL EDTA whole blood or 1 mL EDTA plasma
Minimum Volume
1 mL EDTA whole blood or 0.5 mL EDTA plasma

Billing Information

CPT Code
83090
Pro Fee Code
 
LOINC
2428-1

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.