HLA Antibody Screen Mixed
HLA Antibody Screening Class I & II
HLA Class I Low Resolution
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Molecular Typing (Polymerase Chain Reaction with SSOP) and Solid Phase Assays
In general, HLA matched platelets are used to treat those patients who have a poor response to unmatched platelet transfusions. Using SSOP methodology, HLA Class I typing is performed for the -A, -B, and -C loci. Since the presence of HLA antibodies may have an effect on the survival of platelets after transfusion, antibody screening is performed. PRA indicates the degree of reactivity of tested serum in terms of percent of positive reactions when tested against a panel of known HLA phenotypes.
The patient’s HLA Class I typing will be reported. For positive PRA results, the report will define the detected HLA antibody specificities. For negative results, 0% PRA will be reported.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Collect specimens in sufficient yellow top (ACD) solution A tube AND SST tubes. Send intact specimens at room temperature. Do not refrigerate or freeze.