Days Set Up
Monday - Friday, 8:00am - 4:30pm
Analytic Time

5 days

MiChart Code
Disease Assoc - NARCOLEPSY (HLA-DQB1*0602)
Soft Order Code
NARC

Test Updated:

Synonyms

Narcolepsy - HLA DQB1*0602
HLA DQB1*0602
DQB1*0602 Antigen
TTYPE
TISSUE TYPING
HLA REPORT
NARC
Narcolepsy, HLA
HLA Class II One Locus (High Resolution)

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Test Overview

Test Methodology

Molecular Typing (SSOP)

Test Usage

Narcolepsy is a chronic, debilitating sleep disorder. One of the most important associated genetic factors is the HLA-DQB1*06:02 allele on the DRB1*15:01-DQA1*01:02-DQB1*06:02 haplotype. Between 85 and 95% of narcolepsy patients with cataplexy carry this haplotype. Persons homozygous for HLA-DQB1*06:02 carry a greater risk than heterozygous persons. The detection of HLA-DQB1*06:02 typing is useful as an aid to diagnosis in patients with cataplexy.

Reference Range

Interpretive report will indicate presence or absence of HLA-DQB1*0602.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection

Collect specimen in sufficient yellow top (ACD) solution A or EDTA tubes early in the day. Send intact specimen at room temperature. Do not refrigerate or freeze.

Normal Volume
10 mL ACD (solution A) or EDTA whole blood; additional specimen may be required for patients with extremely low white cell counts.
Minimum Volume
5 mL ACD (solution A ) or EDTA whole blood; additional specimen may be required for patients with extremely low white cell counts.

Billing Information

CPT Code
81376
Pro Fee Code
 
LOINC
 

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.

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