5 days
Test Updated:
Narcolepsy - HLA DQB1*0602
HLA DQB1*0602
DQB1*0602 Antigen
TTYPE
TISSUE TYPING
HLA REPORT
NARC
Narcolepsy, HLA
HLA Class II One Locus (High Resolution)
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Test Overview
Molecular Typing (SSOP)
Narcolepsy is a chronic, debilitating sleep disorder. One of the most important associated genetic factors is the HLA-DQB1*06:02 allele on the DRB1*15:01-DQA1*01:02-DQB1*06:02 haplotype. Between 85 and 95% of narcolepsy patients with cataplexy carry this haplotype. Persons homozygous for HLA-DQB1*06:02 carry a greater risk than heterozygous persons. The detection of HLA-DQB1*06:02 typing is useful as an aid to diagnosis in patients with cataplexy.
Interpretive report will indicate presence or absence of HLA-DQB1*0602.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Specimen Requirements
Collect specimen in sufficient yellow top (ACD) solution A or EDTA tubes early in the day. Send intact specimen at room temperature. Do not refrigerate or freeze.