Bird Shot Retinopathy
Bird Shot Retinopathy - HLA A29
HLA Class I One Locus (Low Resolution)
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Molecular Typing (SSOP)
Birdshot retinopathy is a rare form of posterior uveitis and accounts for 1-3% of uveitis cases in general. Birdshot retinopathy causes severe, progressive inflammation of both the choroid and the retina. Birdshot retinopathy is the disease with the strongest association to a HLA class I antigen, with more than 95% of patients carrying the HLA-A29 antigen. HLA-A*29:02, which is the most frequent A29 allele in the Caucasian population is also the allele most frequently associated with Birdshot retinopathy in Caucasians. The disease has however been observed in HLA*29:01 Caucasian patients.
Interpretive report will indicate presence or absence of HLA-A29.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Collect specimen in sufficient yellow top (ACD) solution A or EDTA tubes early in the day. Send intact specimen at room temperature. Do not refrigerate or freeze.