Days Set Up
Monday - Friday, 8:00am - 4:30pm
Analytic Time

5 days

MiChart Code
Soft Order Code

Test Updated:


HLA Class I One Locus (Low Resolution)
B27 Antigen
HLA B-27
Ankylosing Spondylitis - HLA B27

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Test Overview

Test Methodology

Molecular Typing (SSOP)

Test Usage

The presence of HLA-B27 may help to confirm the diagnosis and aid in treatment of Ankylosing Spondylitis. There is a strong association with the HLA class I molecule HLA-B27, found in 90% of patients with Ankylosing Spondylitis. This association is one of the strongest genetic associations with a common disease, although the mechanism of action remains undefined.

Reference Range

Interpretive report will indicate presence or absence of HLA-B27.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements


Collect specimen in sufficient yellow top (ACD) solution A tubes early in the day. Send intact specimen at room temperature. Do not refrigerate or freeze.

Normal Volume
10 mL ACD (solution A) whole blood; additional specimen may be required for patients with extremely low white cell counts.
Minimum Volume
5 mL ACD (solution A) whole blood; additional specimen may be required for patients with extremely low white cell counts.

Billing Information

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.