1 - 4 days
Test Updated:
Anti-Histone Antibody
Autoantibodies to Histone
Extractable Nuclear Antibody, Histone
HIS
HISTONE ANTIBODY
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Test Overview
Enzyme Immunoassay
Testing for autoantibodies to total histones is useful for evaluating patients suspected of having drug-induced lupus erythematosus (LE). Such patients will usually have a positive test for histone autoantibodies and a negative test for autoantibodies to double stranded DNA (ds-DNA). Patients with idiopathic LE have positive tests for both types of
autoantibodies.
Negative
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Specimen Requirements
Collect specimen in an SST or red top tube.
Collect specimen in an SST or red top tube. Centrifuge, aliquot serum into a plastic vial and refrigerate.
