1 - 4 days
Test Updated:
Anti-Histone Antibody
Autoantibodies to Histone
Extractable Nuclear Antibody, Histone
HIS
HISTONE ANTIBODY
Looking to order a test?
We’ve provided helpful links to make ordering easy.
Find a RequisitionAll specimens should be accompanied by a requisition.
Submitting SpecimensLearn about how to properly label and where to ship specimens.
Order Kits and SuppliesMLabs provides all the supplies necessary for the collection of specimens.
Test FAQVisit our provider FAQ and learn about common questions to ordering tests.
Test Overview
Enzyme Immunoassay
Testing for autoantibodies to total histones is useful for evaluating patients suspected of having drug-induced lupus erythematosus (LE). Such patients will usually have a positive test for histone autoantibodies and a negative test for autoantibodies to double stranded DNA (ds-DNA). Patients with idiopathic LE have positive tests for both types of
autoantibodies.
Negative
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.