Days Set Up
Monday, Wednesday, Friday
Analytic Time

2 - 5 days

MiChart Code
Hexosaminidase A, Total, Leukocytes
Soft Order Code

Test Updated:


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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

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Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

Test FAQ

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Test Overview

Test Methodology

Heat Inactivation, Fluorometric, Automated

Test Usage

Preferred test to order for Tay-Sachs disease, carriers of Tay Sachs, Sandhoff's disease, and carriers of Sandhoff's.

Reference Range

HEXOSAMINIDASE TOTAL, LEUKOCYTES: <=15 yrs: >=20 nmol/min/mg, >=16 yrs: 16.4 - 36.2 nmol/min/mg; HEXOSAMINIDASE PERCENT A, LEUKOCYTES: <=15 yrs: 20 - 80% of total, >=16 yrs: 63 - 75% of total; HEXOSAMINIDASE TOTAL, SERUM: <=15 yrs: >=20 nmol/min/mL, >=16 yrs: 10.4 - 23.8 nmol/min/mL; HEXOSAMINIDASE PERCENT A, SERUM: <=15 yrs: 20 - 90% of total, >=16 yrs: 56 - 80% of total.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

MALES (serum): Collect specimen in a red top tube from a fasting patient. Centrifuge, aliquot serum into a plastic vial and freeze (do not refreeze thawed serum). FEMALES (leukocytes): Collect blood in 7 mL yellow top tube (ACD) solution A or B from a fasting patient. Refrigerate intact ACD tube (frozen ACD tube is unacceptable). ACD specimen must arrive within 48 hours of collection.

Red Top Tube
Normal Volume
Serum: 1 mL serum; Leukocytes: 7.0 mL ACD (solution A or B) whole blood
Minimum Volume
Serum: 0.5 mL serum; Leukocytes: 5.0 mL ACD (solution A or B) whole blood

Billing Information

CPT Code
83080 per specimen
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.