8 hours
Test Updated:
HAMA
Heterophile AB Interferent Scr
Heterophile Interference Screen
Heterophile Ab
Heterophilic Antibody
Heterophile Antibody Screen
Heterophilic Blocking Tube (HBT)
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Test Overview
Sandwich immunoassay with Heterophile Blocking Tube (HBT) pretreatment
A heterophilic sample is a serum or plasma sample containing antibodies which are able to bind to animal antibodies used in immunochemistry assays. The most commonly reported assay interference effect of heterophilic antibodies is a false positive assay result. The Heterophilic Blocking Tube (HBT) allows for the elimination of false positive heterophilic interference in serum or plasma for sandwich immunoassays (e.g., FSH, LH, Prolactin, TSH, Ferritin, CEA, AFP, BHcG, CKMB, CA125 and CA19-9). HBT is a sample pretreatment/second assay intended to confirm or disqualify the original non pretreatment assay result. If the pretreatment result is the same as the original non treated result, the immunochemistry is not affected by a heterophilic antibody interferent in the patient's sample. If the pretreatment sample is lower than the original result, the sample may contain heterophile antibodies affecting the immunoassay and the original result will not be reported.
No heterophilic antibody interference detected.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Specimen Requirements
Collect specimen in an SST (preferred), red top, green top, or lavender top tube. A sandwich immunochemistry assay must be requested on the sample to perform Heterophile Antibody Interferent testing.
