5 - 7 days
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Mutations of the FoxP3 gene have been described in patients with immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX). This assay uses flow cytometry to determine the proportion and intensity of intracellular FoxP3 protein expression in the subset of CD4+ T cells that are CD25 bright and CD127 negative. The PCH101 antibody reacts with the amino terminus of human foxp3 protein.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Collect specimen in lav top tube and send to Specimen Processing at room temperature. Results of current CBC must be sent with specimen.Draw Monday- Thurs only
Collect specimen in lavendar top tube and send intact whold blood specimen at room temperature. Include a copy of the patient's concurrently drawn CBC and Differential result. Draw Monday-Thursday only