Days Set Up
Varies (minimum once per week)
Analytic Time

8 hours

MiChart Code
Fentanyl, Urine Quantitative
Soft Order Code

Test Updated:


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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

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MLabs provides all the supplies necessary for the collection of specimens.

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Test Overview

Test Methodology

UPLC-MS/MS (Ultra-pressure liquid chromatography tandem mass spectrometry)

Test Usage

Fentanyl is potent synthetic opioid analgesic that is used for chronic pain and as an anaesthetic. It has about 100 times the potency of morphine and 50 times that of heroin. Measurement of Fentanyl, and its metabolite Norfentanyl, in urine by UPLC-MS/MS can give clinicians valuable information with regard to monitoring Fentanyl use in pain management. Also, urine levels are important in cases of Fentanyl abuse or overdose.

Reference Range

Negative. Fentanyl: <1.0 ng/mL; Norfentanyl: <10.0 ng/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Collect random urine specimen in clean plastic container

Collection Offsite

Collect random urine specimen in clean plastic container.

Normal Volume
3.0 mL urine
Minimum Volume
1.0 mL urine

Billing Information

CPT Code
Pro Fee Code
Fentanyl: 3637-6; Norfentanyl: 11075-9

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.