Polymerase Chain Reaction (PCR)
Detection or quantitation of HHV-6. Used for monitoring of viral load to track the course of infection and response to treatment. Test detects both Type A and Type B.
2 - 5 days
Blood: Collect specimen in a lavender top (EDTA) tube. Send intact specimen at room temperature (4 - 5 mL). The following specimen types are also acceptable: Bronchial Lavage (BAL) (2 mL in sterile tube, room temperature), Bone Marrow (2 mL in EDTA, room temperature), CSF (2 mL in sterile tube, freeze),and Tissue (moistened with saline, in sterile cup, freeze).
Reactivation of HHV-6 is frequently associated with clinical disease. Direct effects of HHV-6 include fever, rash, hepatitis, encephalitis, pneumonitis and delay or suppression of bone marrow engraftment. Bone marrow suppression by HHV-6 is often confused with rejection in a HSCT patient. Test sent to Viracor-IBT Laboratories.