Days Set Up
Monday, Wednesday, Thursday, 8:00am - 4:00pm
Analytic Time

1 - 2 weeks

MiChart Code
Cytogenetics, Chromosome Analysis/Karyotype, Chorionic Villi
Soft Order Code

Test Updated:


Karyotype, Chorionic Villus Sampling
Karyotype, CVS

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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

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MLabs provides all the supplies necessary for the collection of specimens.

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Test Overview

Test Methodology
Test Usage

Detection of in utero chromosome abnormalities.

Reference Range

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Schedule only through Perinatal counselors 763-4264 for genetic counseling and testing between 8 1/2 to 11 weeks gestation. A Chorionic Villus Sample (CVS) is obtained by the transabdominal or transcervical method. The sample is immediately handed to a Cytogenetic Technologist for processing. Specimens are transported to the laboratory and cultures established within 24 hours of collection. Please complete a MiChart test request and submit it with the specimen. A Cytogenetics Laboratory Requisition is available online at:….

Collection Offsite

Obtain 20 mg to 30 mg of chorionic villus specimen (CVS) by the transabdominal or transcervical method. Transfer the CVS to a Petri dish containing transport medium. Using a stereomicroscope and sterile forceps, assess the quality and quantity of the villi, and remove any blood clots and maternal decidua. Transfer the CVS by using sterile technique to one or two 15-mL centrifuge tube(s) with 15 mL of transport medium. Send specimen refrigerated. Specimen cannot be frozen.

Normal Volume
15-20 mg
Minimum Volume
5 mg

Billing Information

CPT Code
88267 Chromosome Analysis, 88235 Tissue Culture
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.