Chromosome Analysis, Blood for Malignancy
GENERIC CYTOGENETICS TEST
Chromosome Analysis for Hematologic Disorders, Blood
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Cell culture without mitogen stimulation and chromosome analysis. Fluorescence In Situ Hybridization (FISH) when indicated.
Rule out acquired chromosomal abnormalities in chronic and acute leukemia. If the patient has at least 10% blasts (or a combination of blasts, promyelocytes and myelocytes totaling 10%) a peripheral blood sample may be useful, however, note that a bone marrow sample is preferred.
Interpretive report provided.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
If T-cell PLL or other T-cell lymphoproliferative disorder is suspected, contact the laboratory before collecting the specimen. Draw in sodium heparin. Specimen should be drawn and sent during laboratory hours. Patient should not be transfused, leukophoresed or treated. Invert the tube several times to prevent coagulation. Please complete a MiChart test request and submit it with the specimen. A Cytogenetics Laboratory Requisition is available online at: http://www.pathology.med.umich.edu/handbook/Tables/UM_REQ_CYTOGENETICS….
Specimen transport should be arranged so that the specimen is received by MLabs the same day it is collected. Call for a STAT courier if necessary. Alert MLabs if T-cell PLL or other T-cell lymphoproliferative disorder is suspected. Patient should not be transfused, leukophoresed, or treated with antileukemic drugs prior to specimen collection. Collect specimen in a green top (sodium heparin) tube. Invert the tube several times to prevent clotting. Send the specimen intact at room temperature as soon as possible. DO NOT CENTRIFUGE. Clotted samples, samples containing <5 million dividing cells, and samples that are greater than 24 hours old are suboptimal.