Days Set Up
Monday - Friday, 8:00am - 4:00pm
Analytic Time

1 - 2 weeks

MiChart Code
Cytogenetics, Chromosome Analysis/Karyotype, Amniotic Fluid
Soft Order Code

Test Updated:


Karyotype, Amniocentesis

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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

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Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

Test FAQ

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Test Overview

Test Methodology
Test Usage

Detection of in utero chromosome abnormalities.

Reference Range

Interpretive report provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Schedule only through Perinatal counselors 763-4264 for genetic counseling that should begin at 8 - 12 weeks of pregnancy. Discard first mL drawn and change syringe. If specimen is bloody, call the laboratory at 763-5805 to arrange for a STAT courier pick-up. Please complete a MiChart test request and submit it with the specimen. A Cytogenetics Laboratory Requisition is available online at:….

Collection Offsite

Optimal timing for specimen collection is during 16 to 18 weeks of gestation. Draw 20 mL to 25 mL of amniotic fluid in a sterile syringe, discarding the first 2 mL of amniotic fluid. Remove the needle and transfer the specimen to 2 screw-capped, sterile 15-mL clear, conical centrifuge tubes. Send specimen refrigerated. Specimen cannot be frozen.

Normal Volume
20 mL
Minimum Volume
10 mL

Billing Information

CPT Code
88267 Chromosome Analysis, 88235 Tissue Culture
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.