Days Set Up
Analytic Time

2 hours.

MiChart Code
Cystatin C, Serum
Soft Order Code

Test Updated:


Cystatin C

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Test Overview

Test Methodology

Particle Enhanced Immunoturbidimetric Assay (PENIA)

Test Usage

Cystatin C is produced by all nucleated cells at a constant rate and the production rate in humans appears to be constant over the entire lifetime. Elimination from the circulation is almost entirely via glomerular filtration. The serum concentration of Cystatin C is independent of muscle and gender in the age range of 1 to 50 years. It has been proposed that Cystatin C in serum or plasma is a more sensitive marker for GFR and superior to serum creatinine for estimation of GFR. Cystatin C may also be of value as a prognostic marker for acute heart failure.

Reference Range

2-18 years: 0.50 - 1.25 mg/L; 18-60 years: 0.60 - 1.15 mg/L; >60 years: 0.60 - 1.25 mg/L.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Collect specimen in a SST tube.

Collection Offsite

Collect specimen in a SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate. Samples are acceptable for 7 days when stored refrigerated between 2 and 8C.

Yellow Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.25 mL serum

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.