Days Set Up
Monday - Friday
Analytic Time

2 - 10 days

MiChart Code
Cryoglobulin and Cryofibrinogen Panel **Onsite drawstations only - Do Not D
Soft Order Code
CRGSP

Test Updated:

Synonyms

Cryoprecipitate
Cryocrit
CRYFB
Cryofibrinogen
48HRS
7DAYS
Cryoprotien

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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

Learn about how to properly label and where to ship specimens.

Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

Test FAQ

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Test Overview

Test Methodology

Quantitation and Qualitative Typing Precipitation at 1 Degree C.

Test Usage

Evaluating patients with vasculitis, glomerulonephritis, and lymphoproliferative diseases and evaluating patients with macroglobulinemia or myeloma in whom symptoms occur with cold exposure.

Reference Range

CRYOGLOBULIN: Negative (positives reported as a percent). CRYOFIBRINOGEN: Negative. Quantitation and immunotyping will not be performed on positive cryofibrinogen. An interpretive report will be provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Obtain a Thermos with a 37 degrees C warm pack from Specimen Processing by calling 936-6727. Specimens must be maintained at 37 degrees C +/- 2 degrees C from the time they are collected until plasma or serum is separated from the cells. Specimens can be placed in the refrigerator once the serum and plasma have been aliquotted off.

Collection Offsite

Specimens must be maintained at 37 degrees C +/- 2 degrees C from the time they are collected until plasma or serum is separated from the cells.
LAVENDER TOP: Collect specimen in a lavender top tube (plasma gel tube is unacceptable). Blood may be centrifuged immediately in a room temperature centrifuge. If this is not possible, the specimens can be placed in a 37 degrees C waterbath until they can be centrifuged. Specimen should be centrifuged at 37 degrees; ambient is acceptable if 37 degrees is not plausible. Aliquot plasma into a plastic vial. After the plasma is removed, place in the refrigerator; please note on the requisition or as a footnote in the computer that the specimen was processed at 37 degrees C.
RED TOP: Collect specimen in a red top tube (serum separator tube is unacceptable). Within one minute, specimen must be placed into a 37 degrees C +/- 2 degrees C incubator or waterbath. Leave specimen at 37 degrees C until specimen is clotted. Specimen should be centrifuged at 37 degrees; ambient is acceptable if 37 degrees is not plausible. Aliquot serum into a plastic vial. After the serum is removed, place in the refrigerator; please note on the requisition or as a footnote in the computer that the specimen was processed at 37 degrees C.
If the necessary specimen processing equipment is not available, the patient should have the specimen collected at a University of Michigan Taubman Center Blood Drawing station.

Yellow Top Tube
Red Top Tube
Normal Volume
3 mL EDTA plasma AND 5 mL serum (15 mL whole blood in a red top tube)
Minimum Volume
0.5 mL EDTA plasma AND 3 mL serum (10 mL whole blood in a red top tube)

Billing Information

CPT Code
82585, 82595
Pro Fee Code
 
LOINC
 

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.