URINE FREE CORTISOL RESULT
Urinary Free Cortisol
URINE FREE CORTISOL
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Very helpful in evaluating suspected Cushing's syndrome. This test is specific for uncovering elevated urinary unconjugated cortisol. Low values may suggest adrenal insufficiency.
CORTISOL: 0-2 years: not established, 3-8 years: 1.4 - 20.0 mcg/24hours, 9-12 years: 2.6 - 37.0 mcg/24 hours, 13-17 years: 4.0 - 56.0 mcg/24 hours, 18-150 years: 3.5 - 45.0 mcg/24 hours.
CORTISONE: 0-2 years: not established, 3-8 years: 5.5 - 41.0 mcg/24hours, 9-12 years: 9.9 - 73.0 mcg/24 hours, 13-17 years: 15 - 108 mcg/24 hours, 18-150 years: 17 - 129 mcg/24 hours.
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
24 hour urine. Treatment with hydrocortisol should be discontinued at least 2 days prior to this test. Instruct the patient to void at 8:00am and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24 hour collection period, i.e., 8:00am the next morning. Keep urine sample refrigerated. Screw the lid on securely. Transport the specimen promptly to Specimen Processing. Cause for Rejection: Unrefrigerated urine, patient taking hydrocortisone, urine collected in HCl, Na2CO3 or 6N HNO3.
Collect 24 hour urine specimen with no preservative. Aliquot 5 ml into a plastic tube and refrigerate. Record total 24 hour urine volume and collection dates/times on request form. Treatment with hydrocortisol should be discontinued at least 2 days prior to this test.