Days Set Up
Daily, 24 hours
Analytic Time

4 hours

MiChart Code
Soft Order Code

Test Updated:


Cortisol, IVC
Cortisol, Right IVC
Cortisol, Left IVC
Dexamethasone Suppression Test

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All specimens should be accompanied by a requisition.

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Test Overview

Test Methodology

Chemiluminescent Immunoassay (CLIA)

Test Usage

Establish diagnosis of adrenocortical insufficiency, Addison's disease, adrenocortical hypersecretion, or Cushing's disease. Malfunction of any of the organs in the hypothalamus - pituitary - adrenal cortex axis will result in alteration of cortisol levels.

Reference Range

AM: 7.0 - 22.0 mcg/dL; PM: 3.0 - 13.0 mcg/dL.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Collect specimen in SST tube. Blood should be drawn in the morning and late afternoon to evaluate baseline diurnal variation. Time and date of draw must be indicated on requisition.

Collection Offsite

Collect specimen in a red top or SST tube. Centrifuge, aliquot serum into a plastic vial and refrigerate up to 48 hours or freeze for longer storage. Circulating cortisol levels follow a diurnal pattern. Cortisol values are the highest in the morning and lowest in the evening. A single analysis of serum cortisol is of little diagnostic value because of daily variation. Blood should be drawn in the morning and late afternoon to evaluate baseline diurnal variation. Indicate time and date of draw on requisition.

Yellow Top Tube
Normal Volume
0.5 mL serum
Minimum Volume
0.25 mL serum

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.