CAE Total Complement
Functional Complement Assay
Total Active Complement
Total Hemolytic Complement
CAE TOTAL COMPLEMENT (CH50)
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Follow lupus patient's response to therapy; screen for genetic complement component deficiency. Detection of deficiencies and decreased levels of serum complement as seen in renal disease (acute glomerulonephritis, membranoproliferative glomerulonephritis, renal allograft rejection), collagen disease (active systemic lupus erythematosus (SLE), 10% of patients with rheumatoid arthritis (RA), hemolytic anemia (paroxysmal cold hemoglobinuria), hypersensitivity and autoimmune diseases (acute serum sickness, acute vasculitis) as well as subacute bacterial endocarditis, mixed cryoglobulinemia, and advanced hepatic cirrhosis.
41 - 95 U/mL
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
All Michigan Medicine Collection: Collect specimen in a red top or SST tube. Place tube on ice immediately and transport on ice to Specimen Processing. For Health Center Sites, allow to clot at room temperature for 30 minutes, not more than 60 minutes, centrifuge, and aliquot serum and freeze. Cause for Rejection: Specimen off ice longer than 1 hour, serum not separated from red cells within 60 minutes of collection, or serum aliquot refrigerated longer than 48 hours.
MLAB Collection: Collect specimen in a red top or SST tube. Allow the specimen to clot at room temperature for 30 to 60 minutes (65 minutes maximum). Centrifuge and aliquot serum into a plastic vial. Freeze immediately.