Days Set Up
Monday - Friday, 8:00am - 4:30pm; Saturday 8:00am-12:00noon
Analytic Time

8 - 48 hours

MiChart Code
Immunophenotypic Analysis, Plasma Cell Workup, Flow Cytometry
Soft Order Code
PCL

Test Updated:

Synonyms

Plasmacytoma
Plasma Cell Dyscrasia
Immunophenotypic Plasma Cell Panel

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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

Learn about how to properly label and where to ship specimens.

Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

Test FAQ

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Test Overview

Test Methodology

Direct immunofluorescence using flow cytometric techniques.

Test Usage

Confirmation of diagnosis and immunophenotype of plasma cell disorders. See http://www.pathology.med.umich.edu/handbook/Tables/Flow_Cytometry_Panel… for all Flow Cytometry Panels.

Reference Range

Pathologist interpretation of results provided.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Offsite

The following information is required on a Hematopathology Consult requisition:
[list order=Y]
Relevant clinical history
Clinical or morphological findings and suspicions
Specimen source
Date and time of collection
Phone number and after hours pager number for ordering physician
[/list]
[bold]BLOOD:[/bold]
[list]
Collect in a 7-10 ml green sodium heparin Vacutainer® tube and transport at room temperature within 12 hours of collection
Include a copy of the patient's concurrently drawn White Blood Cell and Platelet counts, peripheral blood differential and an unstained peripheral blood smear, OR, concurrently collect a lavender EDTA Vacutainer® tube for a CBCD to be performed upon receipt of the specimen.
[/list]
[bold]BONE MARROW ASPIRATE:[/bold]
[list]
Add 1 - 2 ml of first pull bone marrow aspirate to a green top sodium heparin Vacutainer® tube. Send intact specimen at room temperature within 12 hours of collection.
Include 4 unstained aspirate smears
Include an unstained peripheral blood smear
Include a copy of the patient's most recent White Blood Cell and platelet counts, and peripheral blood differential, OR, concurrently collect a lavender EDTA Vacutainer® tube for a CBCD to be performed upon receipt of the specimen.
[/list]
[bold]BODY FLUID and CSF:[/bold]
[list]
Add body fluid (e.g., CSF, pleural, peritoneal) to a clean, leak proof sterile container and send at room temperature within 12 hours of collection.
Include a a copy of the body fluid cell count and differential.
An original cytospin preparation (preferably unstained) should be included when possible with CSF specimens for correlative morphological evaluation.
[/list]
[bold]BONE MARROW CORE BIOPSY AND FNA:[/bold]
[list]
Submerge in RPMI tissue culture medium (for optimal cell viability) or sterile saline and transport at room temperature within 12 hours of collection.
[/list]
[bold]FRESH TISSUE:[/bold]
[list]
Mince and submerge in RPMI tissue culture medium (for optimal cell viability) or sterile saline, refrigerate, and transport refrigerated within 12 hours of collection.
[/list]

Red Top Tube
Normal Volume
[list]
[bold]BLOOD:[/bold] 7-10 ml
[bold]BONE MARROW ASPIRATE:[/bold] 1-2 ml
[bold]BODY FLUIDS:[/bold] 20-50 ml
[bold]CSF:[/bold] 5-10 ml
[/list]
Minimum Volume
[list]
[bold]BLOOD:[/bold] 1 ml
[bold]BONE MARROW ASPIRATE:[/bold] 1 ml
[bold]BODY FLUIDS:[/bold] 5 ml*
[bold]CSF:[/bold] 1 ml*
[/list]
* The volume of Body Fluids and CSF required is dependent on the cellularity of the specimen.

Billing Information

CPT Code
88184, 88185 x8, 88188
Pro Fee Code
88187.6
LOINC
 

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.