Test Overview
Test Methodology

Automated Liposome Lysis Assay

Test Usage

Diagnosis of C1 deficiency. Investigation of a patient with an absent total complement CH50 level.

Reference Range *

34 - 63 unit/mL

Test Limitations

Absent (or low) C1q functional levels in the presence of normal C1q antigen levels should be replicated with a new serum specimen to confirm that C1q inactivation did not occur during shipping.

Test Details
Days Set Up
Monday - Saturday
Analytic Time

2 - 4 days

Soft Order Code
  • First Component of Complement (subunit C1q)
  • Complement C1Q
Reference Laboratory
Mayo C1QFX (83374)
Special Testing
Specimen Requirements
Collection Instructions

A fasting specimen is preferred but not required. Collect blood in a red top tube; do not use SST tube. Immediately place on wet ice. Centrifuge, aliquot serum into a plastic vial and freeze immediately. Hemolytic or thawed specimens are unacceptable.

Special Handling

Place specimen on wet ice immediately following collection. Must arrive in lab or aliquot and freeze within 15 minutes.

Normal Volume
1 mL serum
Minimum Volume
0.5 mL serum
Rejection Criteria
SST tube not acceptable. Hemolytic or thawed specimens are unacceptable.
Additional Information

Test sent to Mayo Medical Laboratories.

CPT Code
NY State Approved