C1q Complement, Functional

Test Overview

Test Methodology

Automated Liposome Lysis Assay

Test Usage

Diagnosis of C1 deficiency. Investigation of a patient with an absent total complement CH50 level.

Reference Range *

34 - 63 unit/mL

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Limitations

Absent (or low) C1q functional levels in the presence of normal C1q antigen levels should be replicated with a new serum specimen to confirm that C1q inactivation did not occur during shipping.

Test Details

Days Set Up

Monday - Saturday

Analytic Time

2 - 4 days

Soft Order Code

MMLR

Synonyms

First Component of Complement (subunit C1q)
Complement C1Q

Laboratory

Sendout

Reference Laboratory

Mayo C1QFX (83374)

Section

Special Testing

Test Updated

01/13/2021

Update Type

New Tests

Specimen Requirements

Collection Instructions

A fasting specimen is preferred but not required. Collect blood in a red top tube; do not use SST tube. Immediately place on wet ice. Centrifuge, aliquot serum into a plastic vial and freeze immediately. Hemolytic or thawed specimens are unacceptable.

Special Handling

Place specimen on wet ice immediately following collection. Must arrive in lab or aliquot and freeze within 15 minutes.

Rejection Criteria

SST tube not acceptable. Hemolytic or thawed specimens are unacceptable.