Test Overview

Test Methodology

Electrochemiluminescence Immunoassay

Test Usage

An aid in monitoring antiresorptive therapies (eg, bisphosphonates and hormone replacement therapy) in postmenopausal women treated for osteoporosis and individuals diagnosed with osteopenia. An adjunct in the diagnosis of medical conditions associated with increased bone turnover

Reference Range*

MALES: <18 yrs: not established; 18-30 yrs: 120 - 946 pg/mL; 31-50 yrs: 93 - 630 pg/mL; 51-70 yrs: 35 - 836 pg/mL; >70 yrs: not established. FEMALES: <18 yrs: not established; Premenopausal: 25 - 573 pg/mL; Postmenopausal: 104 - 1008 pg/mL.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Test Details

Days Test Performed

Monday - Saturday

Analytic Time

2 - 4 days

Soft Order Code


Test Updated

Update Type: Reference range changed

Updated Date: 06/30/2020



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Laboratory Reference

Mayo CTX (83175)

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Specimen Requirements

Offsite Collection Instructions

Collect specimen in an SST or red top tube from a fasting patient. Centrifuge, aliquot serum into a plastic vial and freeze (preferred) or refrigerate up to 3 days.

Special Handing

Fasting specimen.


Red Top Tube
Yellow Top Tube

Normal Volume

1 mL serum

Minimum Volume

0.8 mL serum

Additional Information

Test sent to Mayo Medical Laboratories.

Billing Information

Fee Codes

CPT Code




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