Days Set Up
Analytic Time

5 - 10 days

MiChart Code
Apolipoprotein E Genotyping
Soft Order Code

Test Updated:


Apo E Genotyping
Apolipoprotein E Genotyping by DNA Analysis
Apo E2 Gene Detection
Apo E3 Gene Detection
Apo E4 Gene Detection
Apolipoprotein E Genotyping

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Find a Requisition

All specimens should be accompanied by a requisition.

Submitting Specimens

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Order Kits and Supplies

MLabs provides all the supplies necessary for the collection of specimens.

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Test Overview

Test Methodology

A PCR-based assay, which includes HhaI digestion of the amplified product, is utilized to identify the 3 most common apolipoprotein E alleles (e2, e3, e4).

Test Usage

Determining the specific apolipoprotein E (APOE) genotypes in patients with type III hyperlipoproteinemia.

Reference Range

Interpretive report provided. This test detects the Apo E2, E3, and E4 genes.

* Reference ranges may change over time. Please refer to the original patient report when evaluating results.

Specimen Requirements

Collection Onsite

Collect blood in a lavender top tube. Refrigerate and send intact blood within 48 hours of collection.

Collection Offsite

Collect blood in a lavender top tube. Refrigerate and send intact blood within 48 hours of collection.

Lavender Top Tube
Normal Volume
3 mL EDTA (lavender) whole blood
Minimum Volume

Billing Information

CPT Code
Pro Fee Code

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Our High Standard

Quality that sets us apart

As the reference laboratory division of Michigan Medicine's Department of Pathology, MLabs shares the institution's commitment to applying established quality principles to clinical laboratory testing. Like other large organizations in complex, consequential fields, we rely on an established approach to monitor quality throughout the testing process.