Hydroxyindoleacetic Acid, 5-
Hydroxytryptamine, 5- Metabolite
5-HYDROXYINDOLEACETIC ACID, U
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High Performance Liquid Chromatography (HPLC)
Aid in the diagnosis of carcinoid tumors.
3 - 10 mg/24 hrs (15.6-52.0 uMol/24 hrs).
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
24 hour urine. Patient should avoid bananas, pineapple, walnuts, chocolate, kiwi, cough medicine and avocados prior to and during collection; also phenothiazines should be withheld for several days prior to collection if possible. Container MUST be labeled with date and time collection started and finished. Instruct the patient to void at 8:00am and discard the specimen. Then collect all urine including the final specimen voided at the end of the 24 hr collection period, ie., 8:00am the next morning. Screw the lid on securely. Transport the specimen promptly to the laboratory. Refrigerate during collection. Non-acidified container (no preservative) is acceptable. If collected in container not containing acid preservative, indicate on container and requisition: "Not Collected in Acid".
Collect 24 hour urine specimen. Add 25 mL of 50% glacial acetic acid (15 mL for pediatric patients) to container prior to start of collection. Following collection, mix well, measure 24 hour urine volume, aliquot 10 mL into a plastic urine container and refrigerate. Record total 24 hour urine volume and collection dates/times on request form. Specimens with no preservative are also acceptable: add 50% glacial acetic acid to container following collection, mix well and send 10 mL aliquot (preferred); alternatively a non-acidified aliquot will be accepted. Patient should avoid bananas, pineapple, walnuts, chocolate, kiwi, cough medicine and avocados prior to and during collection; also phenothiazines should be withheld for several days prior to collection if possible.