This assay is designed to specifically detect IgG-class antibodies to S. mansoni, which are likely cross-reactive to other Schistosoma species. Sensitivity for detection of antibodies to each of the Schistosoma species has not been evaluated for this assay. Patients may remain seropositive by this assay following appropriate treatment and clearance of the infection. Positive results should be confirmed with other laboratory findings (eg, ova and parasite examination), clinical symptoms, and suitable exposure history.