Test Overview
Test Methodology
RT-PCR
Test Usage
CYP2C9 genotype testing is required to determine candidacy and the appropriate maintenance dosage for siponimod before treatment initiation.
Reference Range *
See interpretive report
* Reference ranges may change over time. Please refer to the original patient report when evaluating results.
Test Details
Analytic Time
8 - 12 days
Soft Order Code
LCYP2
MiChart Code
LCYP2
Laboratory
Sendout
Reference Laboratory
Labcorp (512215)
Section
Special Testing
Specimen Requirements
Collection
Collect specimen in 2 EDTA lavender tubes (ACD also acceptable). Send to Specimen Processing as intact whole blood at room temperature. Must be shipped before it is 5 days old.
Alternate Specimen
ACD whole blood
Contraindications
Siponimod is contraindicated in patients who have a CYP2C9*3/*3 genotype.
Normal Volume
5 mL whole blood
Minimum Volume
3 mL whole blood
Storage Temperature
Ambient preferred, refrigerated or frozen acceptable
Rejection Criteria
> 7 day old from collection
Additional Information
Test sent to LabCorp Dublin; performed by Monogram Biosciences