Nature Study Reveals a New Weakness in Aggressive Pediatric Brain Tumors

A team of researchers from the University of Michigan Department of Pathology has identified a previously unknown vulnerability in one of the most aggressive forms of pediatric brain cancer, opening the door to potential new treatment strategies for children with limited therapeutic options.

Drs. Simon Hogan and Nicholas Lukacs Receive Strategic Initiative Fund Award to Establish Michigan Center for Human Immunology Model Systems (Mi-CHIM)

Anew University of Michigan initiative aims to address one of biomedical research’s most persistent challenges: why therapies that succeed in animal models often fail in human patients. Now, a new initiative led by Drs. Simon P. Hogan, the Askwith Research Professor of Food Allergy, Mary H. Weiser Food Allergy Center and Professor of Pathology, and Nicholas W. Lukacs, the Godfrey Dorr Stobbe Professor of Pathology and interim Director of the Mary H. Weiser Food Allergy Center, aims to help close that gap.

Drs. Westerhoff and Kakar Lead New Edition of Diagnostic Pathology: Hepatobiliary and Pancreas

Dr. Maria Westerhoff, alongside Co-Lead Author Dr. Sanjay Kakar of the University of California, San Francisco, has captured the latest advancements in gastrointestinal pathology in the newly published fourth edition of Diagnostic Pathology: Hepatobiliary and Pancreas. Published by Elsevier, the full-color textbook is now available as a comprehensive, expertly curated guide to one of the most challenging areas in pathology.

Cancer Cell Study Identifies Promising New Therapeutic Strategy for Aggressive Neuroendocrine Prostate Cancer

Researchers at the University of Michigan have identified a previously unrecognized survival mechanism in neuroendocrine prostate cancer (NEPC), one of the most aggressive and difficult-to-treat forms of prostate cancer. The findings, which have been published in Cancer Cell, uncover a critical vulnerability in NEPC and suggest a novel dual-targeting strategy that could eventually lead to more effective treatment options for patients with advanced disease.

U-M Pathology Researcher Sriram Venneti, MD, PhD featured in NYT

U-M neuropathologist Sriram Venneti, MD, PhD, was recently featured in The New York Times for his research on diffuse midline glioma (DMG), one of the deadliest pediatric brain cancers. The national feature highlights how his work has helped transform scientists' understanding of the disease and paved the way for new treatment options that are offering hope to children and families worldwide.

Cyclosporiasis Cases Increase in Southeast Michigan: Testing Guidance for MLabs Clinicians

The Michigan Department of Health and Human Services (MDHHS) and local health departments are investigating a recent increase in cyclosporiasis cases, primarily affecting Southeast Michigan counties along the Ohio border. Cyclosporiasis cases typically increase during the summer months; however, the current increase is above expected seasonal incidence. Investigations are underway to identify a potential common exposure or source.

David Manthei, MD, PhD, Named Associate Clinical Pathology Director

By Lynn McCain When Dr. David Manthei talks about his work, one theme comes up again and again: connection. Whether he is bringing together laboratory teams, mentoring residents, or collaborating with clinicians across disciplines, his focus is on strengthening relationships that ultimately improve patient care. Named Associate Director of the Clinical Pathology Division on March 1, 2026, Manthei brings a broad perspective shaped by his many roles. He serves as Section Director of Immunology and Special Chemistry, Associate Program Director for the Pathology Residency Program, Program Director